Postdoctoral Researcher · University of Twente

Medical AI that keeps learning once it reaches the clinic.

I'm Dr. Amin Ranem, a computer scientist in the Mathematics of Imaging & AI group at the University of Twente. I develop risk prediction models for vascular risk prediction in the AI4EVAR project and research continual learning for medical image analysis. My work resulted in 13 publications at venues including CVPR, WACV, MICCAI and in Nature Scientific Reports.

Portrait of Dr. Amin Ranem
NowPostdoc · AI4EVAR
University of Twente
13peer-reviewed publications
Ph.D.Computer Science, TU Darmstadt
38hospitals use AI quality checks I developed for RACOON, Germany's nationwide radiology network
4+invited talks incl. Stanford CNS Lab
About

From continual learning research to AI in the vascular clinic.

I am a Postdoctoral Researcher in the Mathematics of Imaging & AI group at the University of Twente, where I design and develop the AI-based risk prediction models in AI4EVAR, a Dutch multi-center project that personalizes the treatment and follow-up of abdominal aortic aneurysms.

I received my Ph.D. in Computer Science from TU Darmstadt in 2025 with the thesis "Beyond End-to-End — Exploring Extremes in Medical Continual Learning", supervised at the MEC-Lab by Dr. Anirban Mukhopadhyay. My doctoral research explored how segmentation models can keep learning as clinical data shifts. Along the way I worked with transformers, atlas-based methods, Neural Cellular Automata and foundation models like SAM.

Alongside my research, I played a key role in quality assurance for RACOON, Germany's nationwide radiology AI infrastructure connecting 38 university hospitals, and worked on regulatory aspects of continually learning medical software (FDA PCCP). I care deeply about the community side of science: I served on the MICCAI Student Board as Professional Events Officer until 2025 and still co-organize workshops such as DGM4MICCAI and the Data-Centric Dynamic Learning tutorial.

What keeps me in this field is the gap between a good paper and a model a hospital can rely on. Closing that gap takes clean PyTorch code, honest validation and answers a regulator will accept.

At a glance

  • PositionPostdoc, Mathematics of Imaging & AI, University of Twente
  • ProjectAI4EVAR, multi-modal AI prediction models
  • FocusContinual learning · Medical image analysis · Multi-modal AI
  • StackPython · PyTorch · Git · large-scale CT/MRI/CTA pipelines
  • Based inEnschede, the Netherlands
  • LanguagesEnglish & German (native), Arabic, French
  • CommunityMICCAI Student Board · DGM4MICCAI · CapsNetwork
Current Project · ZonMw MedZO

AI4EVAR: personalized aneurysm treatment and follow-up.

Optimizing treatment, patient information and follow-up of abdominal aortic aneurysms across a Dutch clinical–academic consortium.

Every year, around 3,000 abdominal aortic aneurysms in the Netherlands are treated with EndoVascular Aneurysm Repair (EVAR). The procedure is safer up front than open surgery, but 1 in 5 patients needs a re-intervention within five years. Every patient faces lifelong annual imaging, and for most of them it turns out to be unnecessary.

As a postdoctoral researcher on the project, I design, implement and train its two prediction models. They are multi-modal models that combine structured clinical data with CTA imaging, trained on the RADAR database of over 1,000 EVAR patients. The models also embed explainable AI (XAI) modules to provide clinicians with full transparency into how clinical and imaging inputs drive each prediction.

Both models will be tested in a prospective clinical study with around 300 patients across three hospitals. Their outputs feed the project's shared decision tools, from 3D prints and holograms to clinical software, so surgeons and patients can decide on treatment and follow-up together.

Multi-modal AI Risk prediction Clinical data + CTA fusion Explainable AI (XAI) Prospective validation
Model 01 · Preoperative

Optimizing the treatment plan

Predicts the 5-year re-intervention risk of an intended operative plan from preoperative imaging and clinical data. Surgeons can then adjust the stent graft choice or add adjunctive measures before the first incision.

Model 02 · Postoperative

Personalizing follow-up

Extends the first model with procedural and 30-day postoperative data to stratify follow-up: strict surveillance for high-risk patients, far fewer hospital visits for the 60–80% who remain complication-free.

Impact

Less burden, better decisions

Fewer unnecessary scans and visits, lower costs, and predictions patients can actually understand. The tools that carry these predictions are tested with the Harteraad patient panel.

Consortium
  • University of Twente
  • Rijnstate Hospital
  • Medisch Spectrum Twente
  • Elisabeth-TweeSteden Ziekenhuis
  • Tilburg University
  • Pie Medical Imaging
  • Harteraad
Research Interests

What I work on.

Multi-Modal AI

Fusing structured clinical data with CTA imaging into complex predictive systems for vascular risk prediction and EVAR planning.

Continual Learning

Segmentation models that keep learning as scanners, protocols and populations shift, without forgetting what they already know.

Medical Image Segmentation

Robust CT and MRI segmentation across anatomies such as hippocampus, prostate and heart, plus adapting foundation models like SAM to medicine.

Trustworthy & Regulated AI

Quality assurance at national scale (RACOON), explainability, and regulatory pathways for continually learning medical software (FDA PCCP).

Explainable AI (XAI)

Making multi-modal decisions transparent: Showing clinicians how clinical and imaging factors shape each risk prediction.

Neural Cellular Automata

Lightweight, self-organizing models for segmentation and registration, ranging from NCAdapt to NCA-Morph, even trainable on edge devices.

Experience & Education

Where I've been.

Nov 2025 – Present

Postdoctoral Researcher

University of Twente · Mathematics of Imaging & AI · Enschede, NL
  • Postdoctoral researcher in the AI4EVAR project (ZonMw MedZO)
  • Developing & training multi-modal AI models to optimize EVAR treatment, patient information and follow-up
Apr 2022 – Mar 2025 & Jun 2025

Research Assistant

TU Darmstadt · MEC-Lab · Darmstadt, DE
  • Quality assurance for RACOON, the federated learning project across all German university hospitals
  • QA methods for CT/MRI images and segmentation masks
  • Regulatory work on continual learning & software as a medical device (FDA/PCCP)
Oct 2020 – Mar 2022

Student Assistant, RACOON QA

TU Darmstadt · Darmstadt, DE
Nov 2019 – Apr 2020

Business Intelligence Intern

Deutsche Lufthansa AG · Frankfurt, DE
Dec 2018 – Nov 2019

Student Assistant, Prototype Development

German Research Center for Artificial Intelligence (DFKI) · Saarbrücken, DE
2022 – 2025

Ph.D., Computer Science

TU Darmstadt · "Beyond End-to-End — Exploring Extremes in Medical Continual Learning"

2020 – 2022

M.Sc., Business Informatics

TU Darmstadt · "Continual Learning with Transformer Architectures"

2017 – 2020

B.Sc., Business Informatics

Saarland University · "Development of an evaluation tool for time-series analysis of passenger forecasts"

Teaching

  • LecturesAs teaching assistant, I gave lectures in: VAEs (Deep Generative Models) and Registration & Continual Learning (Deep Learning for Medical Imaging)
  • SupervisionB.Sc./M.Sc. theses, research projects & DAAD-WISE interns
Publications

Selected work.

13 peer-reviewed publications, including first-author papers at CVPR, WACV, BMVC and MIDL. Full list is on Google Scholar.

2025

NCAdapt: Dynamic adaptation with domain-specific Neural Cellular Automata for continual hippocampus segmentation

A. Ranem, J. Kalkhof, A. Mukhopadhyay
WACV 2025
2025

FDA's PCCP: Opportunities and Gaps

N. Babendererde, A. Ranem, M. Fuchs, C. Gonzalez, H.J. Krumb, A. Mukhopadhyay
Regulatory Science & Medical Imaging Workshop
2024

NCA-Morph: Medical Image Registration with Neural Cellular Automata

A. Ranem, J. Kalkhof, A. Mukhopadhyay
BMVC 2024 · Oral
2024

Continual atlas-based segmentation of prostate MRI

A. Ranem, C. González, D. Pinto dos Santos, A.M. Bucher, A.E. Othman, A. Mukhopadhyay
WACV 2024
2024

UnCLe SAM: Unleashing SAM's potential for continual prostate MRI segmentation

A. Ranem, M.A.M. Aflal, M. Fuchs, A. Mukhopadhyay
MIDL 2024
2023

Lifelong nnU-Net: a framework for standardized medical continual learning

C. González, A. Ranem, D. Pinto dos Santos, A. Othman, A. Mukhopadhyay
Nature Scientific Reports
2022

Continual hippocampus segmentation with transformers

A. Ranem, C. González, A. Mukhopadhyay
CVPR 2022 Workshops
Invited Talks & Community

Speaking, organizing, giving back.

Nov 2024 · BMVC

Oral Session Talk

"NCA-Morph: Medical Image Registration with Neural Cellular Automata"

Oct 2024 · MICCAI Tutorial

Data-Centric Dynamic Learning, Hands-On

"Continual Learning with UnCLe SAM"

Sep 2024 · Stanford CNS Lab

Invited Talk

"Exploring the extremes of medical continual learning"

Nov 2023 · CapsNetwork

Oral Session Talk

"Beyond E2E continual segmentation"

MICCAI Student Board

Professional Events Officer · 2024 – 2025

I organized the Academia & Industry event, an evening of panels and networking that brought researchers and industry people into the same room.

Workshop & Tutorial Organization

2022 – Present